BACE Inhibition as a Therapeutic Strategy for Alzheimer`s Disease

INVESTIGATING SECONDARY EFFECTS OF BACE1 INHIBITION, A PROMISING THERAPY FOR ALZHEIMER'S DISEASE

Synapses transfer information between neurons in the brain. In Alzheimer’s disease (AD), synapse loss results in dementia therefore it is im..

Function of the Alzheimer protease BACE1 in synapse development.

THE POTENTIAL OF BACE AS A BLOOD BIOMARKER FOR EARLY DETECTION OF ALZHEIMER'S DISEASE

With support from two successive, framework V, EU sponsored consortia, we have developed a targeted immunodeficiency virus-like particle vac..

Role of seizure-related gene 6 in the developing brain cortex

Over the course of evolution, the mammalian brain cortex has become disproportionately large with respect to other brain regions. The dramat..